PReS School Webinar - Update on autoinflammatory diseases: from molecular mechanisms to the clinical picture

Date: 14.04.2025

Tuesday, April 15, 2025 (12:00 to 13:00 CET)

Moderators: 

  • Dr Nuray Aktay Ayaz

I'm a pediatric rheumatologist and head of the Pediatric Rheumatology Department at Istanbul University, Istanbul Medical Faculty. I also coordinate the Master’s Program on Autoinflammatory Diseases, which aligns with my special interest in autoinflammatory diseases and childhood vasculitis. 

In addition to running a highly active outpatient clinic, I have authored over 150 internationally indexed scientific publications in pediatric rheumatology. Since 2023, I have been serving as the Secretary of the Autoinflammatory Diseases Working Group within the Pediatric Rheumatology European Society (PReS), contributing to research and collaboration in this field.

 

  • Dott.ssa Antonella Insalaco

I am a pediatric Rheumatologist, currently works at  the Division of Rheumatology Ospedale Pediatrico Bambino Gesù, Rome, Italy,  where I am in charge of patients admitted to the Paediatric Rheumatology ward.

For the last fifteen years I have devoted a major part of my work to the care of children with autoinflammatory diseases (AID) and currently I am in charge of the AID clinic at my Institution, with more than 250 AID patients in follow-up.

My main area of interest is the identification of pathogenetic mechanisms that underlying the undefined autoinflammatory clinical pictures with the goal to identified novel diseases, to achieve a better stratification of AID patients, a more personalized therapeutic approach, an improvement of long-term outcomes and a reduction of long-term morbidity related to these conditions.


Speakers: 

  • Prof Ivona Aksejentivich

Dr. Ivona Aksentijevich obtained her medical degree from Belgrade University in the former Yugoslavia. In 1990 she joined Dr. Daniel Kastner in the Intramural Research Program of the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) to work as a post-doctoral fellow on the positional cloning of the gene mutated in patients with familial Mediterranean fever (FMF), and later stayed in the same group as a staff scientist. In 2010, she moved with Dr. Kastner to the National Human Genome Research Institute (NHGRI) and continues to study the genetics of monogenic autoinflammatory diseases. Dr. Aksentijevich is certified in clinical molecular genetics by the American Board of Medical Genetics, and supervises a CLIA-certified laboratory for autoinflammatory disease diagnostics in the IDS. Her scientific accomplishements are numerous, and include the identification of several genes underlying known autoinflammatory diseases as well as the discovery of multiple previously unknown conditions. She is a past president of the International Society on Systemic Autoinflammatory Diseases (ISSAID).

 

  • Prof Marco Gattorno

Pediatric Rheumatologist. Head of the Unit of Rheumatology and Autoinflammatory diseases at IRCCS Istituto G. Gaslini in Genoa.

Main scientific interests: clinical and pathogenic characterization of autoinflammatory diseases.  

He is author of 384 full-papers on international journals (H-index 89) and of many book chapters. Editor of the book “Familial Mediterranean Fever” (Springer)

Past- President of the International Society of Systemic Autoinflammatory Diseases (ISSAID).

Past-Chairman of the Working Party for Autoinflammatory diseases of PRES.

From 2008: PI of the “Eurofever” Project (www.printo/eurofever).

From 2017: Responsible for the Autoinflammatory Stream of ERN-RITA

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